At the end of 2018 I received a message from someone who was completely confused when she found out that she had not drank South American Ayahuasca at another provider, but had been given a completely different plant tea.

Since I have worked with the analog in the past and have always been honest about it, I can put myself in her shoes ... without judging the other provider and these amazing plants.

Over the last years I receive more and more questions about the composition of the shamanic tea, so I think this is the perfect opportunity to (re)write this blog about it.

After all, "honesty about what you drink!" is on the website and I fully support that.

Apparently there is a need for transparency and clarity.

To be clear: This blog is for information only.

The answer to the question: Is the use of the name Ayahuasca for analogs just a lack of knowledge or the ease of generalization? And at the same time ... Is it important and if so for whom? I'm not going to give you that answer. I distance myself from unnecessary discussions.

So, what we can find out so far:

The increase in Ayahuasca use has seen tremendous growth in the past 20 years. This is mainly because all kinds of people have been looking for alternative options to cure physical, emotional and mental illness. People felt a greater need to look for solutions outside of the regular care and pharmaceutical options. This unprecedented increase in the use of Ayahuasca is largely led by people from 'our west'.

In addition, there is much to say about mixing thousand-year-old traditions and the Western therapeutic way of meeting many Western needs. You will always find supporters and opponents on this topic.

What we can see is that there are developments in neuroscience research and that may be of interest to those who are more interested in this.

How does it work?

Both the Ayahuasca and the analog version consist of an MAO inhibitor and a DMT component.

Pineal Gland / photo credit: Wikipedia

The liver and stomach ensure that the DMT is normally broken down by so-called MAO enzymes (monoamine oxidase enzymes), so that the DMT cannot reach the brain / pineal gland.

The Banisteriopsis Caapi and the Peganum Harmala contain MAOIs (harmine, harmaline, and tetrahydroharmine). These inhibit the action of the MAO enzymes (3 - 6 hours), which prevents the breakdown of DMT by MAO, so that the DMT can reach the brain and experience the psychedelic effects.

To get a clear picture it is important that you are aware that (and fair is fair) mainly the analog version of Ayahuasca is served in the Netherlands and Europe, with Syrian Rue (also known as Esfand or Peganum Harmala) the MAOI and Mimosa (Jurema) and whether Acacia are the DMT-containing plants.


The Analogues mimic, so to speak, the chemical part of Ayahuasca, namely the MAOI - DMT interaction. While this brew is chemically similar, there are some differences. Perhaps important, or not - you decide that yourself.

Peganum Harmala (photo credit: https://azarius.nl/)

Generally, the Syrian Rue (Peganum Harmala) is used as a Mao inhibitor and Jurema (Mimosa) because it is more accessible and cheaper. This combination is also easier to make.

I speak from experience, because I have worked with the analog for a long time and have been allowed to learn.

After having had several conversations with other facilitators and participants, the MAO inhibitor in the analog would be 'more stable' to experience more psychedelic effects.

Usually the participants feel the first effects within half an hour. The effectiveness of this MAO inhibitor lasts 3-6 hours on average.

In taste it is more bitter due to the high level of tannins and the teachings are given at a rapid pace.

Important note: The Peganum Harmala has been used for thousands of years in the Middle East and around the Mediterranean and is a great teacher!

These plants are very special and powerful teachers and absolutely deserve their respect.

The Vine of Souls

From a shamanic perspective, the Spirit of the Liana / Banisteriopsis Caapi is absent from the Peganum Harmala / Mimosa (Jurema) experience.

The term Ayahuasca comes from Quechua. Aya means soul or spirit and Huasca means rope or vine. Vine of the Soul and (Grand) mother are the most common names. Other names such as Yage, Natema, Dapa, Mihi, Kahi, Pinde, Nixi also refer to the liana.

Vine of the Soul / photo credit: Daphne (Metsa Noma)

When I entered the world of plant medicine, I quickly noticed the attraction to the Ayahuasca vine, or the Banisteriopsis Caapi from South America. The calling to work according to the thousands of years of traditions grew every day. The South American Ayahuasca (MAO inhibitor) is often combined with Chacruna leaves and other DMT containing plants, such as Chaliponga, Jurema etc.

From a chemical perspective, the Banisteriopsis Caapi vine has higher levels of tetrahydroharmine. When investigated and these compounds isolated, these alkaloids were called 'telepathins' because of their ability to induce telepathic properties in humans.

The ingredients are very high in terms of cost.

Making the Ayahuasca takes about 5 days.

For me, although strong, the taste is better to drink than the Peganum Harmala.

The intensity of the experience can be strong (er).

While a journey can also be experienced as much more peaceful and clear.

The journey itself can last well into the night without a real set time limit.

I find myself in the Student's position and the medicine is more likely in a teaching modus to me.

It can vary greatly from person to person.

By the way, did you know that many tribes in the Amazon work with the Banisteriopsis Caapi vine on their own without DMT-containing additives? Why? -> She is the actual Medicine.

In addition, Ayahuasca is part of healing processes and in addition to many plant medicines (purgatives / purifications) and strict diets are applied and observed in order to heal.